Coming soon from Popcap, the insanely successful developers of casual games like Bejewelled and Peggle, is Plants vs Zombies.
It looks somewhat like a Tower Defense style game, where you add different sorts of cannons and other weapons to a winding path that advancing enemy hordes stream down but who can say for sure.
All I know is that they have a hella catchy promotional music video which is rather cute (and features zombies with butter on their head)